Pharmaceutical Sciences Research

Caleb Class
Assistant Professor of Pharmaceutical Sciences
317-940-9831, cclass@butler.edu, Office PHSB363

Understanding genomic data through bioinformatics can help us solve some of the most complicated medical problems of our time. Dr. Class’s research involves the data mining and analysis of metabolomic, genomic, and other data to identify potential cancer treatment strategies. Research projects also include the development of new bioinformatics software that allows any researcher to more easily understand complicated biological data. View Dr. Class’s Publications on Google Scholar.

Nandita G. Das, PhD, RPh
Professor of Pharmaceutical Sciences (Pharmaceutics)
317-940-9015, ndas@butler.edu, Office PHSB355

Dr. Nandita Das’ research involves targeted delivery of siRNA against neurodegenerative diseases such as Alzheimer’s and Huntington’s disease, and modulation of Multi-Drug Resistance (Pgp and MRP) in cancer. Specifically, Dr. Das’ research projects involve fabrication and characterization of lipospheres and liposomes for nanomedicine applications. View Dr. Nandita Das’ Nanomedicine Research Page.

Sudip K. Das, PhD
Professor of Pharmaceutical Sciences (Pharmaceutics)
317-940-9134, sdas@butler.edu, Office PHSB353

Dr. Sudip Das’ research involves nanotechnology approaches in targeted delivery of siRNA and small molecule drugs for the treatment of cancer. Specifically, Dr. Sudip Das’ research projects involve fabrication and characterization of polymer nanoparticles for nanomedicine applications. View Dr. Sudip Das’ Nanomedicine Research Page.

Alexandre M. Erkine, PhD
Professor of Pharmaceutical Sciences (Bioinformatics & Mol. Biology)
317-940-8569, aerkine@butler.edu, Office PHSB359

Bioinformatics including machine learning combined with methods of modern molecular biology is a powerful tool. Combination of these methods allows to take a fresh look at fundamental problems of biochemistry and pharmacology. View details of Dr. Erkine’s publications.

Hala Fadda, PhD, MRPharmS
Professor of Pharmaceutical Sciences (Pharmaceutics)
317- 940-8574, hfadda@butler.edu, Office PHSB357

Dr. Fadda’s research focuses on bridging the physical and biological sciences in the field of pharmaceutics to gain a better understanding of drug bioavailability and some of the reasons behind the intra- and inter-individual variability in drug exposure. Focus on gastrointestinal physiology to set up an in vitro drug release model that better simulates the diverse and dynamic nature of our guts in different patient populations.

Alican Gulsevin, PhD
Assistant Professor of Pharmaceutical Sciences
317-940-5791, agulsevin@butler.edu, Office PHSB365

W. Conrad Hong, PhD
Associate Professor of Pharmaceutical Sciences (Pharmacology)
317-940-9580, chong@butler.edu, Office PHSB351

Dr. Hong’s research focuses on the investigation of signaling mechanisms of dopamine in the brain, particularly the dopamine transporter (DAT), a membrane carrier uniquely expressed on dopamine neurons. DAT and its close homologs (the serotonin transporter and norepinephrine transporter) are important targets of therapeutic agents such as antidepressants and ADHD medications, and abused psychostimulants cocaine and methamphetamine.

C. Patience Masamha, PhD
Associate Professor of Pharmaceutical Sciences (Pharmacology)
317-940-6428, cmasamha@butler.edu, Office PHSB361

Understanding the molecular mechanisms that are involved in oncogenesis is critical in identifying biomarkers for early disease detection and in the development of targeted anti-cancer therapeutics. Projects use techniques of next-generation sequencing technologies, bioinformatics  and  a wide array of molecular biology techniques to study the global RNA transcriptome, identify genes that are altered in cancer and elucidate the molecular mechanisms involved in the process. View Dr. Masamha’s publications.