Alumni & Parent Programs

Dr. Stanley T. Crooke '66

Robert Todd Duncan Alumni Achievement Award, 1999

Dr. Cooke is founder, chairman and chief executive officer of Isis Pharmaceuticals.  Isis is a development stage biopharmaceutical company that focuses on a new paradigm in drug discovery, antisense oligonucleotides.  Since Dr. Crooke and his colleagues founded Isis in 1989, the company has grown rapidly, completing its initial public offering in May 1991.  The company reports broad progress in antisense technology and its rapid conversion to therapeutic product opportunities.  Isis was the first company to commercialize an antisense drug and has achieved a number of important corporate collaborative relationships.

Dr. Crooke is a member of the board of directors of SIBIA (LaJolla, Calif.), GeneMedicine, Inc. (Houston, Texas), EPIX Medical, Inc. (Cambridge, Mass.) and Idun Pharmaceuticals (LaJolla, Calif.). He is a member of the IBC Advisory Council, Current Drugs Advisory Board, the Editorial Advisory Board of the Journal of Drug Targeting and Antisense Research and Development and the Editorial Board of Gene Therapy and Molecular Biology. He has been appointed by the American Association for Cancer Research to serve as a member of the California State Legislative Committee.

Before founding Isis, Dr. Crooke was president of research and development for SmithKline Beckman Corporation (SKB) where he directed the activities of nearly 3,000 scientists, physicians and support staff for the SmithKline & French Laboratories, the pharmaceutical arm of SKB.

Prior to joining SKB, Dr. Crooke helped establish the anticancer drug discovery and development program at Bristol Myers, which succeeded in bringing to market a significant number of drugs. At Bristol, he established numerous licensing and collaborating agreements and developed the Bristol-Baylor Laboratory.

During his illustrious career, Dr. Crooke has supervised the development of 17 drugs currently on the market and others in development. In addition to his involvement in the pharmaceutical industry, Dr. Crooke also maintains active academic positions. He is an adjunct professor at the University of California-San Diego and San Diego State University. He has won numerous teaching awards and has authored over 400 publications and edited 18 books. He is active in molecular and cellular biology and pharmacology of antisense oligonucleotides.

Dr. Crooke received a bachelor's degree in pharmacy from Butler in 1966. He went on to do post-graduate and doctoral work at Baylor College of Medicine in Houston, Texas, earning a Ph.D. in 1971 and an M.D. in 1974. He has served on the Partnership for Excellent Alumni Campaign National Honorary Committee as well as the College of Pharmacy Board of Visitors for Butler.

Updated 1999